112 Best Grey’s Anatomy Trivia

For the fans of the longest-running medical drama, here are 110+ trivia questions to test your knowledge and challenge your friends to be crowned a super fan of this 18-season-long, so far, series. Shonda Rhimes has been delivering a ton of twists, turns, and drama-filled episodes throughout the series, we have tried to condense all of this into these questions that will put your love for the series to the test. So, gather your friends and family and enjoy.

Q1: Name “The Seattle Grace Five”?

Show Answer
Meredith, Cristina, Arizona, Derek, Mark.

Q2: Who’s seat did Arizona take on the plane that crashed?

Show Answer
Alex.

Q3: What is the middle name of Meredith’s son Derek?

Show Answer
Bailey.

Q4: What specialty was ben before he went into General Surgery?

Show Answer
Anesthesia.

Q5: Who officiated Callie and Arizona’s wedding?

Show Answer
Bailey.

Q6: What did Izzie do before becoming a Surgical Resident?

Show Answer
Modeling.

Q7: Who did Richard choose to be his legal guardian for medical diseases?

Show Answer
Meredith.

Q8: Who won the Gray Sloan Surgical Innovation contest?

Show Answer
No one, Bailey canceled it.

Q9: What was April Kepner’s specialty?

Show Answer
Trauma Surgery.

Q10: What specialty was Meredith pursuing before General Surgery?

Show Answer
Neurosurgery.

Q11: What did the surgeons fail to do to save Derek’s life?

Show Answer
Burr holes/CT Scan.

Q12: What country did April go to with the army?

Show Answer
Jordan.

Q13: Throughout the series, who does Owen Hunt get married to?

Show Answer
Cristina, Amelia, and finally Teddy.

Q14: What is Owen Hunt’s army rank in the series?

Show Answer
Major.

Q15: What pose does Amelia do before surgery?

Show Answer
Superhero pose.

Q16: What were the names of Mark Sloan’s daughters?

Show Answer
Sophia and Sloan.

Q17: Who among the characters grew up on a farm?

Show Answer
April Kepner.

Q18: Who does April finally lose her virginity to?

Show Answer
Jackson.

Q19: Other than Amelia name one of Derek’s sisters?

Show Answer
Nancy, Liz, and Kathleen.

Q20: How many Half-Sisters does Meredith have?

Show Answer
3 (Molly, Lexie, and Maggie).

Q21: Who did George cheat on Callie with?

Show Answer
Izzie stevens.

Q22: Who was the source of the Syphilis that George got from the nurse?

Show Answer
Alex.

Q23: Who did Meredith date along with Derek?

Show Answer
The veterinarian Finn.

Q24: What was the metal in Richard’s hip that was poisoning him?

Show Answer
Cobalt.

Q25: Where does Cristina move to follow the 10th Season?

Show Answer
Switzerland.

Q26: Where do Jo and Alex end up getting married?

Show Answer
On a Ferry.

Q27: What other Shows are in the Greys Anatomy universe?

Show Answer
Private Practice and Station 19.

Q28: How did the interns after the original five practice surgery?

Show Answer
By doing it on each other and corpses.

Q29: How did Alex discover he had an arrhythmia?

Show Answer
Cristina accidentally jabbed him with an epi needle.

Q30: How did the hospital discover that George is John Doe?

Show Answer
He traced 007 on Meredith’s hand and Callie confirmed he had a birthmark.

Q31: What specialty does Jo Wilson shift to in the later seasons?

Show Answer
Obs and Gyne.

Q32: What was Jo Wilson’s name before she changed it?

Show Answer
Brooke Stadler.

Q33: Who does Meredith end up giving the sparkler pager to?

Show Answer
Cristina.

Q34: How many seasons is greys anatomy now?

Show Answer
18.

Q35: In season 18 where does Meredith do her research on Parkinson’s?

Show Answer
Minnesota.

Q36: In what season does Jackson go back to see his father?

Show Answer
Season 17.

Q37: Which characters does Meredith meet during her COVID Coma?

Show Answer
George, Derek, Lexie, Mark, and Deluca.

Q38: What nickname does Owen give to Cristina and Meredith?

Show Answer
The twisted sisters.

Q39: What was the name of Teddy’s lover before 9/11?

Show Answer
Allison.

Q40: What was Amelia addicted to?

Show Answer
Opioids (Morphine).

Q41: How did Izzie have Alex’s kids?

Show Answer
She used the frozen embryos from when she had cancer.

Q42: Why was George leaving the Hospital before he died?

Show Answer
Because he joined the army.

Q43: What was Alex’s mom working as when they reunited?

Show Answer
She was working as a librarian.

Q44: What is the ER known as in the series?

Show Answer
The pit.

Q45: Name two main characters who had cancer on the show?

Show Answer
Izzie, Nicole Herman, Atticus Lincoln, Catherine Fox.

Q46: On what did Meredith and Derek write their wedding vows?

Show Answer
On a blue post-it note.

Q47: Which spirits are seen in the “Day of the Dead” episode?

Show Answer
Derek, Alex, Mark, Elis Grey, and the dog Mac.

Q48: Why did Stephanie leave the hospital?

Show Answer
She wanted to explore and travel as she has been in a hospital her entire life.

Q49: How does Jo’s ex-husband die?

Show Answer
He slipped and hit the bed frame causing brain death.

Q50: Who is Owen’s best man at his wedding to Amelia?

Show Answer
April.

Q51: Who is the song “How to save a life” by?

Show Answer
The Fray.

Q52: Where did Cristina meet Dr. Thomas before Minnesota?

Show Answer
He was her examiner during the boards.

Q53: Who was the doctor that failed his/her boards?

Show Answer
Dr. April.

Q54: During the alternate reality episode who was the Chief of Staff?

Show Answer
Dr. Ellis Grey

Q55: During the alternate reality episode who did Alex cheat on Meredith with?

Show Answer
April Kepner.

Q56: What condition do Meredith and Riggs make up to get Megan’s kid to the US?

Show Answer
Beta Thalassemia.

Q57: Why did Cristina quit surgery?

Show Answer
She developed PTSD from the shooting incident.

Q58: Who are the Mercy West residents?

Show Answer
Jackson, April, Reed, and Charles.

Q59: Who’s the doctor that gets fired after the Mercy West merger?

Show Answer
Dr. Izzie Stevens.

Q60: What does Izzie do with Denny’s money?

Show Answer
Gives it to Bailey to build The Denny Duquette Memorial Clinic.

Q61: Why does Cristina lose in the Harper Avery Awards?

Show Answer
Because the hospital has connections with the Harper Avery Foundation.

Q62: What organ does Meredith donate to her father?

Show Answer
Part of her Liver.

Q63: Why was April fired from the Hospital?

Show Answer
Because she was not focused on her patient and the patient died.

Q64: Which department did the residents hang out in when they needed peace and quiet?

Show Answer
The Dermatology department.

Q65: Who was the Cardio Goddess?

Show Answer
Teddy Altman as Cristina described her.

Q66: What was the name of the procedure that involved 6 kidney transplants?

Show Answer
The Domino surgery.

Q67: Where are Meredith’s mother’s ashes spread?

Show Answer
In the scrub room.

Q68: What was the name of the hospital at the start of the series?

Show Answer
Seattle Grace Hospital.

Q69: Regarding trauma center classes, what class is the hospital?

Show Answer
Class 1 Trauma Center.

Q70: What was the name of Alex’s brother?

Show Answer
Aaron.

Q71: Who drops a kidney during the Domino surgery?

Show Answer
Meredith.

Q72: What does Bailey scream after the kidney is dropped?

Show Answer
5-SECOND RULE!

Q73: What does Bokhee work as in the hospital?

Show Answer
She works as a scrub nurse.

Q74: Who does Lexie hit with a softball during the match between hospitals?

Show Answer
Mark’s girlfriend Julia.

Q75: Who is the coach of the hospital’s softball team?

Show Answer
Owen.

Q76: Which hospital do they play against?

Show Answer
Seattle Presbyterian Hospital.

Q77: Where do Callie and George get married?

Show Answer
Las Vegas.

Q78: In season 2, why does Cristina have surgery?

Show Answer
Due to having an ectopic pregnancy.

Q79: When was the first time Meredith almost died?

Show Answer
Season 2, when she stuck her hand to hold a bomb.

Q80: Who pulled Meredith out when she drowned?

Show Answer
Derek pulled her out of the water.

Q81: Who operated on Derek when he was shot?

Show Answer
Cristina and Jackson.

Q82: What did Bailey tell the Clark shooter to escape?

Show Answer
That she was a nurse.

Q83: What is the name of Maggie’s new husband?

Show Answer
Winston Ndugu.

Q84: From what did Maggie’s mother die?

Show Answer
Breast Cancer.

Q85: Where do Callie and Arizona move to?

Show Answer
New York.

Q86: What does Ben Warren do after he quits surgery?

Show Answer
He becomes a firefighter.

Q87: What is Arizona’s specialty?

Show Answer
A Pediatric and Fetal Surgeon.

Q88: What is the promise that Callie breaks to Arizona?

Show Answer
The promise not to amputate her leg.

Q89: What is the name of the condition that Arizona develops due to her leg being cut off?

Show Answer
Phantom Limb Syndrome.

Q90: What does Deluca’s father suffer from?

Show Answer
Bipolar Disorder.

Q91: Who had Deluca been in a romantic relationship with before his debut in the show?

Show Answer
Sam Bello.

Q92: Who does Carina Deluca marry?

Show Answer
Maya Bishop (From Station 19).

Q93: How did Cristina Yang refer to her interns?

Show Answer
By numbers.

Q94: What was Lexie Grey’s nickname?

Show Answer
Lexiepedia.

Q95: What were Lexie’s last words?

Show Answer
“Meant to be”

Q96: What season does Mark Sloan die?

Show Answer
Season 9.

Q97: Who does April end up marrying?

Show Answer
Mathew.

Q98: What condition does Bailey develop after the infection issue?

Show Answer
OCD.

Q99: Who’s the doctor that complained to HR regarding Dr. Arizona?

Show Answer
Leah Murphy.

Q100: Where do Richard and Catherine get married?

Show Answer
In the hospital chapel.

Q101: In season 12, why does Meredith almost die?

Show Answer
She is attacked by a patient.

Q102: Who does Alex beat up in the season 12 finale?

Show Answer
Andrew Deluca.

Q103: What is Carina Deluca’s research interest?

Show Answer
Female orgasms.

Q104: Where do Megan and Nathan move to?

Show Answer
Malibu.

Q105: How young was Maggie when she finished Med school?

Show Answer
19.

Q106: Who does Teddy marry before Owen?

Show Answer
Henry, to secure his medical insurance.

Q107: What type of car did Derek drive?

Show Answer
A Porsche.

Q108: Why did Derek and Amelia’s dad get shot?

Show Answer
He refused to give up his watch to a mugger, a watch given to him by their mother.

Q109: Who is Meredith’s emergency contact?

Show Answer
Alex.

Q110: What was Bailey worried about regarding the kid stuck in concrete?

Show Answer
His bladder exploding.

Q111: Who were Meredith’s first roommates?

Show Answer
Izzie and George.

Q112: Who bought Meredith’s mother’s house?

Show Answer
Alex.
Obadah Qandil
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